I'm loving it so far, though I am not completely without complaint.
1. Lack of hotkeys. This slows everything down, both the mage build and the archery oriented warrior build I've started
2. Fencing stolen goods. Now, don't get me wrong, not being able to sell goods you stole would be realistic, if you could, say, go to another town to sell them. How does somebody in whiterun know a random potion I stole in another town is stolen? It should only apply to the town you stole it from, IMO.
3. I could be wrong about this, but past games show that the enemies scale with you. You also level up every 5 or 6 skill increases. Now, correct me if I'm wrong because I could be, but if you are constantly levelling up from non-combat skills, what happens when you have to fight the scaled up enemies when you're stuck with very low level combat capabilities?
4. Giants. What's the deal? Why are 10 foot tall humanoids stronger than 10 ton dragons? The one time I tried fighting a giant, not only did he one shot me, but he LITERALLY knocked me into orbit. I'm pretty sure my character's corpse hit the upper limit of the sky.